There are only a relatively small number of different ligand binding pockets.

The binding pocket of the 5-methoxy group is more investigated than the other pocket.

Pharmaceutical companies already use computers to design drugs that can fit into the binding pocket of a protein.

The binding pockets are showed in figure 2.

As one can see, the anchor residues fit nicely into the binding pockets.

Thus, the mutation would not directly influence the binding pocket for either ligand.

Aromatic residues lining the binding pocket are shown in purple.

The active site is composed of a shallow-substrate binding pocket including -1 and +1 subsites.

The important amino acids in the binding pocket for this group differ between the two receptors.

It presents a very limited level of flexibility and fits tightly into the receptor's binding pocket.

Firstly, there is high shape complementarity between the binding pocket and biotin.

As such, the nucleotide binding pocket remains that most amenable to inhibitor generation.

These similar binding pockets suggest that the two riboswitches have undergone convergent evolution.

CCR5 antagonists are very different in shape and electrostatic potential although they all share the same binding pocket.

A conserved N-terminal domain contributes residues to the 8-oxoguanine binding pocket.

Mutants were also engineered site-specifically to test the role of key residues in or near the binding pocket.

The difference is probably because of the size and other physical properties of the ions and the binding pocket.

The structure also identified a hydrophobic binding pocket for lipid binding.

The naphthoate conjugate is clearly accommodated within the binding pocket of the apoprotein.

The binding pocket of LeuT contains two metal binding sites.

The insertion and removal of metals from the binding pocket of clathrochelates can be very slow.

This is because more Van der Waals interactions can occur between sugar and binding pocket.

The beta-propeller fold is important in fucose recognition; five binding pockets are found between the propeller blades.

The binding pocket contains metal ion (zinc and magnesium) binding sites.

The binding pockets of various receptors differ greatly, depending on the size and shape of the ligands.