Visual impairment including optic atrophy may be seen in affected patient.

Optic atrophy occurs in the first year and the following symptoms show up before thirteen years.

Progression of dominant optic atrophy varies even within the same family.

Optic atrophy may also occur, often leading to blindness.

Children of patients should be screened regularly for visual changes related to dominant optic atrophy.

An example of this phenomenon is Leber optic atrophy.

Progressive optic atrophy may result in decreased visual acuity or color vision.

In some cases, Dominant optic atrophy may remain subclinical until early adulthood.

By exclusion chlorambucil was the most likely cause of this patient's visual failure and optic atrophy.

Motor skills and speech are lost, and optic atrophy causes blindness.

Manipulation of the optic atrophy 1 (Opa1) gene had interesting effects on fusion between mitochondria.

Nanri suffered a sudden onset of optic atrophy in 1953 and nearly lost his sight.

Cyanocobalamin can cause severe and swift optic atrophy, but other forms of vitamin B are available.

Other findings include chorioretinal scars, and optic atrophy.

A Nigerian study showed other complications include secondary glaucoma, hyphaema, and optic atrophy.

Dominant optic atrophy is inherited in an autosomal dominant manner.

This typically evolves to very severe optic atrophy and permanent decrease of visual acuity.

If papilledema is protracted, it may lead to visual disturbances, optic atrophy, and eventually blindness.

It is characterized by optic atrophy followed shortly by loss of hearing and peripheral neuropathy.

In the later onset form, patients typically have normal intellectual function, but present with spastic diplegia and optic atrophy.

Longstanding papilledema leads to optic atrophy, in which the disc looks pale and visual loss tends to be advanced.

There is interaction with ATP synthase and the optic atrophy protein.

Costeff optic atrophy syndrome is another name for 3-methylglutaconic aciduria type III.

We report a patient with visual failure and optic atrophy who was receiving long term chlorambucil for a low grade non-Hodgkin's lymphoma.

Loss of tissue in the optic nerve of the eye (optic atrophy)